Young Min Kim Selected Research

YS 49

9/2014	CKD712, a synthetic isoquinoline alkaloid, enhances the anti-cancer effects of paclitaxel in MDA-MB-231 cells through regulation of PTEN.
3/2013	(S)-1-α-naphthylmethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712), promotes wound closure by producing VEGF through HO-1 induction in human dermal fibroblasts and mouse skin.
12/2009	Upregulation of PTEN by CKD712, a synthetic tetrahydroisoquinoline alkaloid, selectively inhibits lipopolysaccharide-induced VCAM-1 but not ICAM-1 expression in human endothelial cells.
8/2009	(S)-1-(alpha-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712) reduces rat myocardial apoptosis against ischemia and reperfusion injury by activation of phosphatidylinositol 3-kinase/Akt signaling and anti-inflammatory action in vivo.

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Young Min Kim Research Topics

Disease

38	Neoplasms (Cancer) 05/2022 - 10/2006
16	Inflammation (Inflammations) 01/2020 - 10/2008
12	Colonic Neoplasms (Colon Cancer) 06/2016 - 10/2006
11	Sepsis (Septicemia) 01/2018 - 09/2009
8	Carcinogenesis 03/2022 - 10/2006
7	Hypoxia (Hypoxemia) 06/2016 - 01/2007
6	Neoplasm Metastasis (Metastasis) 07/2018 - 09/2008
6	Ischemia 01/2012 - 10/2008
5	Infections 01/2018 - 08/2011
5	Myocardial Ischemia (Ischemic Heart Diseases) 01/2012 - 10/2008
4	Wounds and Injuries (Trauma) 09/2021 - 11/2009
4	Atherosclerosis 04/2012 - 09/2008
4	Reperfusion Injury 01/2012 - 10/2008
4	Infarction (Infarctions) 08/2009 - 10/2008
3	Stomach Neoplasms (Stomach Cancer) 05/2022 - 10/2021
3	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 08/2009
3	Human Influenza (Influenza) 05/2019 - 06/2011
3	Heart Arrest (Cardiac Arrest) 09/2018 - 02/2013
3	Colorectal Neoplasms (Colorectal Cancer) 05/2011 - 10/2006
2	Azoospermia 01/2022 - 01/2017
2	Ileus 10/2021 - 10/2021
2	Communicable Diseases (Infectious Diseases) 03/2021 - 05/2014
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 02/2019 - 04/2016
2	Fibrosis (Cirrhosis) 11/2018 - 10/2016
2	Chronic Hepatitis B 11/2018 - 12/2012
2	Hepatocellular Carcinoma (Hepatoma) 02/2018 - 03/2016
2	Lung Neoplasms (Lung Cancer) 08/2017 - 04/2013
2	Insulin Resistance 10/2016 - 04/2010
2	Obesity 10/2016 - 04/2010
2	Breast Neoplasms (Breast Cancer) 10/2014 - 03/2009
2	Septic Shock (Toxic Shock Syndrome) 01/2013 - 09/2009
1	Cyanosis 02/2022
1	Methemoglobinemia 02/2022
1	Poisoning 02/2022
1	Precancerous Conditions 01/2022
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2022

Drug/Important Bio-Agent (IBA)

12	HMGB1 Protein (HMG1)IBA 05/2018 - 04/2011
10	Proteins (Proteins, Gene)FDA Link 10/2021 - 10/2008
8	Glucose (Dextrose)FDA LinkGeneric 03/2022 - 04/2010
7	Pharmaceutical PreparationsIBA 10/2021 - 02/2005
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 08/2009
6	CytokinesIBA 07/2017 - 07/2009
6	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2015 - 03/2007
5	RNA (Ribonucleic Acid)IBA 05/2022 - 01/2020
5	Triglycerides (Triacylglycerol)IBA 03/2022 - 10/2016
5	Heme Oxygenase-1IBA 11/2017 - 09/2007
5	AlkaloidsIBA 11/2017 - 11/2012
5	AMP-Activated Protein KinasesIBA 01/2007 - 10/2006
4	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 11/2012
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2016 - 09/2008
4	YS 49IBA 09/2014 - 08/2009
3	Small Interfering RNA (siRNA)IBA 01/2022 - 06/2020
3	Therapeutic UsesIBA 01/2022 - 01/2007
3	LipopolysaccharidesIBA 01/2020 - 01/2011
3	Antiviral Agents (Antivirals)IBA 11/2018 - 12/2012
3	NF-kappa B (NF-kB)IBA 01/2017 - 02/2009
3	Fluorouracil (Carac)FDA LinkGeneric 08/2015 - 03/2007
3	QuercetinIBA 04/2014 - 03/2009
3	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 04/2012 - 09/2008
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2011 - 10/2006
3	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2007 - 12/2006
2	Formaldehyde (Formol)FDA Link 05/2022 - 05/2021
2	Antisense OligonucleotidesIBA 01/2021 - 04/2019
2	AntibodiesIBA 01/2021 - 01/2018
2	entecavir FDA Link 11/2018 - 12/2012
2	Sirtuin 1IBA 01/2018 - 10/2016
2	Monoclonal AntibodiesIBA 01/2018 - 06/2008
2	1,2,3,4-tetrahydroisoquinolineIBA 11/2017 - 01/2013
2	Indicators and Reagents (Reagents)IBA 08/2017 - 10/2014
2	Carrier Proteins (Binding Protein)IBA 10/2016 - 05/2011
2	isoquinolineIBA 10/2016 - 09/2014
2	p38 Mitogen-Activated Protein KinasesIBA 07/2016 - 05/2013
2	SeleniumIBA 03/2016 - 10/2006
2	AntioxidantsIBA 03/2016 - 08/2009
2	ResveratrolIBA 08/2015 - 01/2007
2	Paclitaxel (Taxol)FDA LinkGeneric 09/2014 - 02/2005
2	Prostate-Specific Antigen (Semenogelase)IBA 09/2013 - 08/2009
2	EnzymesIBA 09/2012 - 08/2009
2	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 01/2012 - 09/2007
2	Anti-Bacterial Agents (Antibiotics)IBA 08/2011 - 09/2009
2	TristetraprolinIBA 05/2011 - 04/2010
2	thiamine triphosphorate (TTP)IBA 05/2011 - 04/2010
2	Capsaicin (Zostrix)FDA Link 04/2010 - 01/2007
2	Prostaglandins EIBA 12/2009 - 10/2008
2	Anthocyanins (Anthocyanin)IBA 11/2009 - 10/2008
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2009 - 04/2008
2	Etoposide (VP 16)FDA LinkGeneric 03/2007 - 01/2007
2	Adenosine Monophosphate (AMP)IBA 01/2007 - 01/2007
1	WD repeat containing planar cell polarity effectorIBA 05/2022
1	ParaffinIBA 05/2022
1	MethemoglobinIBA 02/2022
1	Methylene Blue (Methylthioninium Chloride)FDA Link 02/2022
1	Sodium NitriteIBA 02/2022

Therapy/Procedure

13	Therapeutics 01/2022 - 01/2007
3	Drug Therapy (Chemotherapy) 05/2022 - 06/2008
3	Induced Hypothermia 09/2018 - 02/2013
2	Gastrectomy 10/2021 - 05/2016
2	Stents 05/2020 - 02/2005
2	Radiotherapy 07/2018 - 06/2008
2	Catheters 12/2011 - 10/2008